You may report side effects to the FDA at 1-800-FDA-1088. Some medicines may affect the progestogen-only pill's effectiveness – ask your doctor for details. Uncommon side effects of desogestrel may include vaginal infection, contact lens intolerance, vomiting, hair loss, dysmenorrhea, ovarian cysts, and fatigue, while rare side effects include rash, urticaria, and erythema nodosum. "Product Information. WebMD does not provide medical advice, diagnosis or treatment. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Call your doctor for medical advice about side effects. This risk increases with age and with heavy smoking (15 or more cigarettes per day) and is quite marked in women over 35 years of age. Selected from data included with permission and copyrighted by First Databank, Inc. Applies to desogestrel / ethinyl estradiol: oral tablet. In Meyler's Side Effects of Drugs (Sixteenth Edition), 2016. Water Retention Ortho Pharmaceutical Corporation, Raritan, NJ. Ethinylestradiol is a synthetic oestrogen with similar effects as estradiol. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Semisynthetic progestogens Desogestrel. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use. Call your doctor for medical advice about side effects. Cerner Multum, Inc. "UK Summary of Product Characteristics." Desogestrel is a progestogen structurally related to levonorgestrel. using the desogestrel-only pill, are listed in the manufacturers’ product characteristics.6 In a randomised trial the most commonly reported side effects were headache, acne, breast pain, nausea, vaginitis and dysmenorrhoea.7 The incidence of these side effects was similar in desogestrel … Total and free plasma T were reduced by approximately 30%. Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Coronavirus in Context: Interviews With Experts, Sign Up to Receive Our Free Coroanvirus Newsletter, Blood Clot In A Deep Vein Of The Extremities, A Yeast Infection Of The Vagina And Vulva, Altered Interest In Having Sexual Intercourse, Increased Sensitivity Of The Skin To The Sun, A Blockage Of The Bile Duct That Resulting In High Bilirubin Levels, A Clot In The Small Veins That Carry Blood To Or From The Retina Of The Eye, A Significant Type Of Allergic Reaction Called Anaphylaxis, A Type Of Allergic Reaction Called Angioedema, Abnormal Bleeding In The Brain Resulting In Damage To Brain Tissue, Called A Hemorrhagic Stroke, Benign Hepatic Cell Adenoma, A Type Of Liver Tumor, Cervical Dysplasia, The Development Of Abnormal Cells In The Cervix, Clouding Of The Lens Of The Eye Called Cataracts, Focal Nodular Hyperplasia Of Liver, A Type Of Liver Tumor, Hemolytic Uremic Syndrome, A Condition That Affects The Kidney And The Blood, Inflammation Of The Liver Called Hepatitis, Obstruction Of A Blood Vessel By A Blood Clot, Sudden Blindness And Pain Upon Moving The Eye, A Change In The Curvature Of The Cornea Of The Eye, A Decrease In How Often A Woman Menstruates, Breastmilk Production Not Associated With Childbirth Or Nursing, Ectropion Of Cervix, Where Cells Normally Inside The Cervix Spread To The Outer Cervical Surface, Erythema Multiforme, A Type Of Allergic Skin Reaction, Erythema Nodosum, A Skin Condition With Red And Painful Nodules, Fluid Retention In The Legs, Feet, Arms Or Hands, Hirsutism, A Condition Of Hair Growth On Parts Of The Body Normally Without Hair. © 2005 - 2019 WebMD LLC. These side effects may go away during treatment as your body adjusts to the medicine. If experienced, these tend to have a Less Severe expression 1. If you notice any other effects, check with your healthcare professional. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. [Ref], Common (1% to 10%): Breast pain/tenderness, amenorrhea, irregular bleeding, Uncommon (0.1% to 1%): Breast enlargement/hypertrophy, metrorrhagia, Rare (0.01% to 0.1%): Vaginal/breast discharge, vaginal candidiasis, Frequency not reported: Breakthrough bleeding, spotting, menstrual flow change, cervical ectropion and secretion, temporary infertility (after discontinuation), vaginitis, candidiasis, lactation diminution, premenstrual syndrome, dysmenorrhea, endometriosis, uterine myoma[Ref], Common (1% to 10%): Nausea, abdominal pain, Uncommon (0.1% to 1%): Vomiting, diarrhea, Frequency not reported: Gallbladder disease, mesenteric thrombosis, gastrointestinal symptoms (e.g., abdominal pain, cramps, bloating), pancreatitis, colitis, Crohn's disease, ulcerative colitis[Ref], Common (1% to 10%): Depressed mood, altered mood, Uncommon (0.1% to 1%): Decreased libido, nervousness, Frequency not reported: Depression/mental depression[Ref], Frequency not reported: Stroke, transient ischemic attack, cerebral hemorrhage/thrombosis, chorea exacerbation, Sydenham's chorea, epilepsy[Ref], Frequency not reported: Decreased serum folate, porphyria exacerbation, decreased carbohydrate tolerance, increased/decreased folate[Ref], Uncommon (0.1% to 1%): Rash/allergic rash, urticaria, acne, Rare (0.01% to 0.1%): Erythema nodosum/multiforme, pruritus, alopecia, hirsutism, Frequency not reported: Scalp hair loss, melasma/chloasma or persistent melasma/chloasma, gestational herpes gestationis, hemorrhagic eruption[Ref], Uncommon (0.1% to 1%): Hypertension, fluid retention/edema, Rare (0.01% to 0.1%): Arterial/venous thromboembolism, Frequency not reported: Myocardial infarction, venous thrombosis, arterial/venous thromboembolic disorders, varicose vein aggravation, thrombophlebitis and venous thrombosis with/without embolism[Ref], Rare (0.01% to 0.1%): Contact lens intolerance, cataract, Frequency not reported: Retinal thrombosis, optic neuritis, partial/complete vision loss, corneal curvature change/steepening[Ref], Frequency not reported: Anaphylactic/anaphylactoid reactions, hereditary angioedema/angioedema, severe reactions with respiratory and circulatory symptoms[Ref], Frequency not reported: Cholestatic jaundice, Budd-Chiari syndrome, acute/chronic liver function disturbances, liver tumors/hepatic adenomas or benign liver tumors[Ref], Frequency not reported: Hormone-dependent tumors, breast cancer[Ref], Frequency not reported: Cystitis-like syndrome, impaired renal function[Ref], Frequency not reported: Pulmonary embolism[Ref], Frequency not reported: Hemolytic uremic syndrome[Ref], Frequency not reported: Systemic lupus erythematosus[Ref].